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KMID : 1202020140070020167
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Journal of Korean Thyroid Association
2014 Volume.7 No. 2 p.167 ~ p.171
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Analysis of Therapeutic Modalities of Thyroid Cancer in Koreabetween 2008 and 2012
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Seo Gi-Hyeon
Chung Jae-Hoon
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Abstract
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Background and Objectives: The incidence of thyroid cancer has been increasing in Korea as well as in othercountries. The majority of thyroid cancers are papillary thyroid carcinomas and follicular thyroid carcinomas,both of which are classified as differentiated thyroid carcinoma (DTC). Total or near-total thyroidectomyfollowed by administration of radioactive iodine (RAI) constitutes the initial treatment for DTC. This study wasconducted to investigate the therapeutic modalities of surgery and RAI for the treatment of DTC in Korea usingclaims data provided by the Health Insurance Review and Assessment Service.
Materials and Methods:Thisstudy was performed in 170,131 (men 29,002, women 141,129) Korean patients with thyroid cancer treated fromJanuary 2008 to December 2012. Patients with past history of thyroid cancer prior to 2008 were not included.
Results: Total or near total thyroidectomy was done in 83.4%, lobectomy in 14.4%, and subtotal thyroidectomyin 2.2%. Postoperative RAI treatment was performed in 52.7%. Median 100 mCi of RAI was administered atmedian 89 days after operation, and it was completed with one dose in 66.0%. Thirty mCi was mostly preferredas an initial dose in 35.6%, and subsequently 150 mCi in 25.7%, 100 mCi in 17.5%, and more than 150 mCi in10.1%. Median cumulative RAI dose was 130 mCi. RAI treatment rate was decreasing during recent 5 years.
Conclusion: This is the first nationwide report to investigate the therapeutic modalities of surgery and RAI forthe treatment of DTC in Korea.
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KEYWORD
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Thyroid cancer, Thyroidectomy, Radioactive iodine
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